Microbiological Hydroxylations: Myths and Realities

Authors

  • Robert Azerad

DOI:

https://doi.org/10.2533/chimia.1993.93

Abstract

Microorganisms such as filamentous fungi are known to carry out regio- and stereoselective hydroxylations of a wide range of natural or synthetic hydrophobic organic compounds, probably as part of a detoxification mechanism. The potential and limitations of such reactions, as a tool for performing preparative hydroxylation and functionalization, will be examined through selected examples: a quinidine derived alkaloid, a monoterpenic prochiral compound (1,8-cineole), and synthetic polyclic enones.

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Published

1993-04-28