Artificial Ribonucleases

Authors

  • Robert Häner Department of Chemistry and Biochemistry, University of Bern, Freiestr. 3, 3012 Bern

DOI:

https://doi.org/10.2533/chimia.2001.1035

Keywords:

Artificial ribonucleases, Lanthanide complexes, Oligonucleotide, Rna, Rna cleavage

Abstract

Chemically modified oligonucleotides serve as tools in fundamental research as diagnostic reagents and pharmaceutical compounds. Various chemical groups can nowadays be linked to oligonucleotides, In particular, synthetic constructs of oligonucleotides and lanthanide complexes can serve as artificial ribonucleases. In this paper, some applications of modified oligonucleotides originating from our research efforts directed at the development of artificial ribonucleases are summarized.

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Published

2001-12-19

How to Cite

[1]
R. Häner, Chimia 2001, 55, 1035, DOI: 10.2533/chimia.2001.1035.

Issue

Vol. 55 No. 12 (2001): The Department of Chemistry and Biochemistry of the University of Bern

Section

Scientific Articles

License

Copyright (c) 2001 Swiss Chemical Society

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.