Medicinal Applications of Metal–Peptide Bioconjugates

Authors

  • Nils Metzler-Nolte

DOI:

https://doi.org/10.2533/chimia.2007.736

Keywords:

Bioconjugates, Bioorganometallic chemistry, Ferrocene, Peptides, Solid-phase synthesis

Abstract

Organometal–peptide bioconjugates have a variety of applications in biomedical studies, such as antiproliferative and anti-bacterial activity, as well as to aid the elucidation of the mode of action of the conjugated metal complexes. Our group has developed the solid-phase synthesis of organometal–peptides by different synthesis schemes, their characterization and use in biomedical studies. Selected examples are presented in this review.

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Published

2007-11-28

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Section

Scientific Articles