Biologically Relevant Small Radicals

Georg Bauer; Gabor Speier; Gabor Merenyi; Jozsef Kaizer; Sara Goldstein; Bernard T. Golding; Georg Gescheidt; Lidia Gebicka; Jerzy L. Gebicki; Chryssostomos Chatgilialoglu; Peter Wardman

doi:10.2533/chimia.2008.704

Biologically Relevant Small Radicals

Authors

Georg Bauer
Gabor Speier
Gabor Merenyi
Jozsef Kaizer
Sara Goldstein
Bernard T. Golding
Georg Gescheidt
Lidia Gebicka
Jerzy L. Gebicki
Chryssostomos Chatgilialoglu
Peter Wardman

DOI:

https://doi.org/10.2533/chimia.2008.704

Keywords:

Antioxidants, Reactive carbon species, Reactive oxygen species, Reactive nitrogen species, Reactive sulfur species, Signaling pathways

Abstract

Biologically relevant small radicals are at the focus of the working group 4 (WG4) of the COST Action CM0603 (Free Radicals in Chemical Biology, CHEMBIORADICAL). This article surveys the areas of research being undertaken by the partners in WG4. The character of the radicals is described together with experimental techniques utilized to follow their structure and reactivity. Specifically, C-, S-, N- and O-centered radicals of small size, and their interaction with different biomolecules are described. Processes at the molecular level exemplifying important biological signaling and damaging pathways are introduced.

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Published

2008-09-24

How to Cite

[1]

G. Bauer, G. Speier, G. Merenyi, J. Kaizer, S. Goldstein, B. T. Golding, G. Gescheidt, L. Gebicka, J. L. Gebicki, C. Chatgilialoglu, P. Wardman, Chimia 2008, 62, 704, DOI: 10.2533/chimia.2008.704.