Bachem – Insights into Innovative and Sustainable Peptide Chemistry and Technology by the Leading Independent Manufacturer of TIDES

Sandip Jadhav; Wolfgang Seufert; Carolin Lechner; Ralph Schönleber

doi:10.2533/chimia.2021.476

Bachem – Insights into Innovative and Sustainable Peptide Chemistry and Technology by the Leading Independent Manufacturer of TIDES

Authors

Sandip Jadhav Bachem AG, Hauptstrasse 144, CH-4416 Bubendorf, Switzerland
Wolfgang Seufert Bachem AG, Hauptstrasse 144, CH-4416 Bubendorf, Switzerland
Carolin Lechner Bachem AG, Hauptstrasse 144, CH-4416 Bubendorf, Switzerland
Ralph Schönleber Bachem AG, Hauptstrasse 144, CH-4416 Bubendorf, Switzerland;, Email: ralph.schoenleber@bachem.com

DOI:

https://doi.org/10.2533/chimia.2021.476

PMID:

34233807

Keywords:

Bachem, Molecular hivingtm, Peptide apis, Spps, Sustainable processes

Abstract

Since its foundation in 1971, Bachem has grown sustainably over the last 50 years and is excellently positioned as the leading company for the development and production of TIDES i.e. peptides and oligonucleotides. Bachem's success relies on its commitment to manufacturing high-quality active pharmaceutical ingredients (APIs) alongside its continual passion for innovative chemistry and technologies. This review aims at summarizing improvements in high-quality peptide manufacturing as well as recent advances towards sustainable and innovative technology in peptide chemistry, thereby reducing the environmental footprint.